Geri Dön

Bacterial thermotaxis by speed modulation

Başlık çevirisi mevcut değil.

PDF İndir

  1. Tez No: 402025
  2. Yazar: MAHMUT DEMİR
  3. Danışmanlar: YRD. DOÇ. DR. HANNA SALMAN
  4. Tez Türü: Doktora
  5. Konular: Biyokimya, Fizik ve Fizik Mühendisliği, Biochemistry, Physics and Physics Engineering
  6. Anahtar Kelimeler: Belirtilmemiş.
  7. Yıl: 2013
  8. Dil: İngilizce
  9. Üniversite: Unıversıty Of Pıttsburgh
  10. Enstitü: Yurtdışı Enstitü
  11. Ana Bilim Dalı: Belirtilmemiş.
  12. Bilim Dalı: Belirtilmemiş.
  13. Sayfa Sayısı: Belirtilmemiş.

Özet

Özet yok.

Özet (Çeviri)

One of the most important factors that affects bacterial migration and is sensitive to thermal changes is the bacterial swimming speed controlled by the rotation of the flagellar motors. In the natural habitats of bacteria, gradients often extend over relatively long distances such that their steepness is too small for bacteria to detect. We studied the bacterial behavior in such thermal gradients and found that they migrate along shallow thermal gradients due to a change in their swimming speed resulting from the effect of temperature on the intracellular pH. When nutrients are scarce the bacteria's intracellular pH and consequently the swimming speed decreases with increasing temperature, which causes them to drift towards the warm end of the gradient. However, when serine is added to the medium at concentrations >300M, the intracellular pH increases causing the swimming speed to increase continuously with increasing temperature, and the bacteria to drift towards the cold end of the gradient. This directional migration is not a result of bacterial thermotaxis in the classical sense, because the steepness of the gradients is below the sensing threshold of bacteria. Nevertheless, our results show that the directional switch requires the presence of the bacterial sensing receptors which seem to be involved in regulating the intracellular pH. Additionally, it is also important to understand how thermal fluctuations and rate of thermal changes experienced by bacteria during their excursion in natural environments affect their run speed. To this end we have studied the dynamics of the bacterial flagellar motor's speed in response to thermal fluctuations by tethering bacteria to a glass surface through their flagella. Our results show that under heavy load the response of the motor to fast linear thermal changes is instantaneous. However, when subjected to thermal fluctuations with varying frequency, they exhibit a resonant response to specific frequencies reflecting the complex internal dynamics of the motor.

Benzer Tezler

  1. Tez No

    56778

    Bacterial colonization on dental implant materials

    Diş implant materyalleri üzerindeki bakteriyal kolorizasyon

    GÜL KAHVECİ

    Yüksek Lisans

    İngilizce

    İngilizce

    1996

    BiyolojiOrta Doğu Teknik Üniversitesi

    Biyoloji Ana Bilim Dalı

    PROF. DR. GÜRDAL ALAEDDİNOĞLU

  2. Tez No

    58584

    Bacterial cloning and expression of BRCAZ encoded proteins

    BRCAZ geninin bakteriye klonlanıp ekspresyonu

    A.EMRE SAYAN

    Yüksek Lisans

    İngilizce

    İngilizce

    1997

    Biyolojiİhsan Doğramacı Bilkent Üniversitesi

    Biyoloji Ana Bilim Dalı

    PROF. DR. MEHMET ÖZTÜRK

  3. Tez No

    90689

    Bacterial production and screening of polyhdroxyalkanoates by using a novel spectrofluorometric method

    Polihidroksialkanoatların bakteriyel üretimi ve yeni spektroflorometrik bir metod olarak nil kırmızısı kullanılarak izlenmesi

    BARIŞ EMRE DAYANÇ

    Yüksek Lisans

    İngilizce

    İngilizce

    1999

    BiyolojiOrta Doğu Teknik Üniversitesi

    Biyoloji Ana Bilim Dalı

    PROF. DR. GÜRDAL ALAEDDİNOĞLU

    PROF. DR. VASIF NEJAT HASIRCI

  4. Tez No

    112051

    Bacterial adhesion to solid surface and its prevention by the application of silver

    Bakterilerin katı yüzeylere tutunması ve gümüş uygulanması ile önlenmesi

    WASSIM MOHAMAD AMINE EL-SOUFI

    Yüksek Lisans

    İngilizce

    İngilizce

    2001

    Tıbbi BiyolojiBoğaziçi Üniversitesi

    Biyomedikal Mühendisliği Ana Bilim Dalı

    PROF. DR. SABRİ ALTINTAŞ

  5. Tez No

    297807

    Bacterial uptake mechanism of peptides investigated by steered molecular dynamics simulations

    Peptitlerin bakteri hücresine alınım mekanizmasının yönlendirilmiş moleküler dinamik simülasyonlar ile incelenmesi

    İHSAN ÖMÜR AKDAĞ

    Yüksek Lisans

    İngilizce

    İngilizce

    2011

    BiyoteknolojiBoğaziçi Üniversitesi

    Hesaplamalı Bilimler ve Mühendislik Ana Bilim Dalı

    YRD. DOÇ. ELİF ÖZKIRIMLI ÖLMEZ

Geri Dön