ineklerde değişik yollardan ve farklı dozda verilen PGFz alfa'nın fertilitiye etkisi
Effects of PGFz alfa (dalmazin R) administered in different routes and various doses on fertility in cows
- Tez No: 138280
- Danışmanlar: PROF. DR. HAKKI İZGÜR
- Tez Türü: Doktora
- Konular: Veteriner Hekimliği, Veterinary Medicine
- Anahtar Kelimeler: Cows, Fertility, PGFax, Cows, Fertility, PGFax
- Yıl: 2003
- Dil: Türkçe
- Üniversite: Ankara Üniversitesi
- Enstitü: Sağlık Bilimleri Enstitüsü
- Ana Bilim Dalı: Veterinerlik Doğum ve Jinekolojisi Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: Belirtilmemiş.
Özet
55 SUMMARY Effects of PGF2a (Dalmazin®) administered in different routes and various doses on fertility in cows The aim of study was to evaluate the effect of administration of PGF2a via different routes and various doses on fertility parameters in cows and usebility of these PGF^ programs in practice. Material of the study was fifty Holstein cows between days 45-60 pospartum belongs to Ankara Bala Tarım işletmesi. Cows were randomly devided into 5 grups. Cows in grup I (n:10) were administered 0,150 mg of D- Cloprostenol intramuscularly and artificial inseminated at detected oestrus. Cows in which oestrus was not detected were administered a second D- Cloprostenol injection, in the same route and doses, 14 days after the first injection and artificial inseminated at 48 and 72th hours following the second administration. Cows in grup II (n:10) were injected 0,150 mgD-Cloprostenol 14 days apart and artificial inseminated at 48 and 72th hours following the without detetion of oestrus behaviors. Cows in grup III (n:10) were reduced doses of D-Cloprostenol intravulvosubmucosal cows detected in oestrus were inseminated, which did not reveal oestrus behaiors were administered a second D-Cloprostenol injection, in the same route and dose, 14 days following the first administration and artificial inseminated at 48 and 72th hours after the second D-Cloprostenol injection without detection. Cows in grup IV (n:10) administered reduced doses of D-Cloprostenol intravulvosubmucosally 14 days apart and artificial insemination performed at 48 and 72th hours folowing the second injection. The remaining cows (n:10) were used as control grup. Blood samples of each animal were taken prior to PGF20 administrations and at the time of artificial insemination for P4 assays. The rates of luteolizis following the second D-Cloprostenol injection were 100% for I and II. grups, 80% for grups III and IV. Oestrus detetion rates following the treatments were 40% and 50% for grups I and II, respectively, intervals between the end of treatment and detection of oestrus were found to be 3,25±1,25 days in grup I and 5,20±3,42 for grup III. These results did not reveal a statistically important difference (P>0,05). Pregnancy rates achived by inseminations at detected oestrus were 75% and 40% for I and III grups, respectively. Total pregnancy rate were 60% in grups I and III, 70% in grups II and IV and 50% in control grup. Intervals between the end of treatment and conception were 10,16+10,36, 12,42±17,3, 15,00±16,43, 21,85±20,21 days for the treatment grups, respectively. This intervals was 37,80±15,80 days for the control grup. There was not a ststistically important difference between the control grups. However, the difference between the treatment grups and the control grup56 was statistically important (P<0,05). The calving- pregnancy intervals were 68,66+14,33, 74,57±16,49, 69,50±20,21, 83,42+18,98, and 89,00+17,05 days for the grups I, II, III, IV and the control grup, respectively. Pregnancy index were calculated as 1,3 in grups I and III, 1,8 in control grup and grup IV and 1,4 in grup II. It was found that, both intramuscular and intravulvosubmucosal injections of PGFza in the aim of sexuel synchronization could be used and the fertility parameters obtain are close to each other. In addition, treatments in grup II and IV are found to be more profitable in practice.
Özet (Çeviri)
55 SUMMARY Effects of PGF2a (Dalmazin®) administered in different routes and various doses on fertility in cows The aim of study was to evaluate the effect of administration of PGF2a via different routes and various doses on fertility parameters in cows and usebility of these PGF^ programs in practice. Material of the study was fifty Holstein cows between days 45-60 pospartum belongs to Ankara Bala Tarım işletmesi. Cows were randomly devided into 5 grups. Cows in grup I (n:10) were administered 0,150 mg of D- Cloprostenol intramuscularly and artificial inseminated at detected oestrus. Cows in which oestrus was not detected were administered a second D- Cloprostenol injection, in the same route and doses, 14 days after the first injection and artificial inseminated at 48 and 72th hours following the second administration. Cows in grup II (n:10) were injected 0,150 mgD-Cloprostenol 14 days apart and artificial inseminated at 48 and 72th hours following the without detetion of oestrus behaviors. Cows in grup III (n:10) were reduced doses of D-Cloprostenol intravulvosubmucosal cows detected in oestrus were inseminated, which did not reveal oestrus behaiors were administered a second D-Cloprostenol injection, in the same route and dose, 14 days following the first administration and artificial inseminated at 48 and 72th hours after the second D-Cloprostenol injection without detection. Cows in grup IV (n:10) administered reduced doses of D-Cloprostenol intravulvosubmucosally 14 days apart and artificial insemination performed at 48 and 72th hours folowing the second injection. The remaining cows (n:10) were used as control grup. Blood samples of each animal were taken prior to PGF20 administrations and at the time of artificial insemination for P4 assays. The rates of luteolizis following the second D-Cloprostenol injection were 100% for I and II. grups, 80% for grups III and IV. Oestrus detetion rates following the treatments were 40% and 50% for grups I and II, respectively, intervals between the end of treatment and detection of oestrus were found to be 3,25±1,25 days in grup I and 5,20±3,42 for grup III. These results did not reveal a statistically important difference (P>0,05). Pregnancy rates achived by inseminations at detected oestrus were 75% and 40% for I and III grups, respectively. Total pregnancy rate were 60% in grups I and III, 70% in grups II and IV and 50% in control grup. Intervals between the end of treatment and conception were 10,16+10,36, 12,42±17,3, 15,00±16,43, 21,85±20,21 days for the treatment grups, respectively. This intervals was 37,80±15,80 days for the control grup. There was not a ststistically important difference between the control grups. However, the difference between the treatment grups and the control grup56 was statistically important (P<0,05). The calving- pregnancy intervals were 68,66+14,33, 74,57±16,49, 69,50±20,21, 83,42+18,98, and 89,00+17,05 days for the grups I, II, III, IV and the control grup, respectively. Pregnancy index were calculated as 1,3 in grups I and III, 1,8 in control grup and grup IV and 1,4 in grup II. It was found that, both intramuscular and intravulvosubmucosal injections of PGFza in the aim of sexuel synchronization could be used and the fertility parameters obtain are close to each other. In addition, treatments in grup II and IV are found to be more profitable in practice.
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