Periodontal and dental health parameters in chronic renal failure and renal transplant patients receiving immunosuppressive therapy
Başlık çevirisi mevcut değil.
- Tez No: 11429
- Danışmanlar: DOÇ. DR. FERİHA ÇAĞLAYAN
- Tez Türü: Doktora
- Konular: Diş Hekimliği, Dentistry
- Anahtar Kelimeler: Böbrek nakli, Böbrek yetmezliği-kronik, Periodontoloji, İmmünosüpresyon, Kidney transplantation, Kidney failure-chronic, Periodontology, Immunosuppression
- Yıl: 1989
- Dil: İngilizce
- Üniversite: Hacettepe Üniversitesi
- Enstitü: Sağlık Bilimleri Enstitüsü
- Ana Bilim Dalı: Periodontoloji Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: Belirtilmemiş.
Özet
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Özet (Çeviri)
61 SUMMARY The periodontal and dental health of 54 renal transplant recipients and 52 chronic renal failure patients- on hemodialysis were evaluated and compared to that of systemically healthy subjects matched for age, sex, social status and the number of teeth present. Renal transplant recipients had gone transplantation at least nine months prior to the study and had a stable renal function during the last three months. These patients were on an immunosuppressive (I.S. ) drug therapy regimens since the time of transplantation. Both 'of the renal patient groups had significantly higher plaque index scores than the respective controls. By contrast, the renal transplant recipients showed significantly lower periodontal scores and pocket depths. However, there was no significant difference between the hemodialysis group and their healthy control regarding the mean periodontal index scores and pocket depths. DMF Scores were found less in hemodialysis group than the control group. Despite the abundant local plaque accumulations in both of the renal patient groups, no significant differences could be found among the three groups regarding the mean sulcular bleeding index scores, gingival index scores and increase in gingival hyperplasia. Renal transplant recipients62 displayed the game tmean DMF scores when compared to their matched controls. Among the 44 patients on cyclosporin therapy gingival hyperplasia was observed in 14 patients. Gingival hyperplasia could not be noticed in any of the patients on azathioprine therapy. There was a significant correlation between the occurance of gingival hyperplasia and the plaque index scores in patients receiving cyclosporin therapy. Neither, the periodontal health parameters, nor the incidence of gingival hyperplasia seemed to be significant correlated with the duration of i.S. therapy. A poor correlation found between the plaque index scores and the periodontal destruction in chronic renal failure patients may implicate an inhibition in the inflammatory reaction and/or immune response. Variations among the groups studied may suggest the modulation of periodontal condition, both by general health status in chronic renal failures and the I.S. agents used in renal transplant recipients.
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